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1

p16INK4a expression in cytology of ascites and response to chemotherapy in advanced ovarian cancer

Tomoko Goto, Masashi Takano, Junko Hirata, Toshiyuki Kohno, Shigenori Ohtsuka, Keiichi Fujiwara, Hitoshi Tsuda

Journal:

International Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 313 KB

english, 2009

2

Large scale synthesis of oligoribonucleotides on a solid support: synthesis of a catalytic RNA duplex

Shigenori Iwai, Toshiro Sasaki, Eiko Ohtsuka

Journal:

Year:

1990

Language:

english

File:

PDF, 947 KB

english, 1990

3

Synthesis of oligoribonucleotides by the phosphoramidite approach using 5′-levulinyl and 2′-tetrahydrofuranyl protection

Shigenori Iwai, Eiko Ohtsuka

Journal:

Tetrahedron Letters

Year:

1988

Language:

english

File:

PDF, 288 KB

english, 1988

4

Solid-phase synthesis of protected oligonucleotide blocks : Applications to block condensation on a polymer support and synthesis of a 3'-modified oligonucleotides

Shigenori Iwai, Makoto Koizumi, Morio Ikehara, Eiko Ohtsuka

Journal:

Year:

1987

Language:

english

File:

PDF, 627 KB

english, 1987

5

Synthesis and hybridization studies on two complementary nona(2'-O-methyl)ribonucleotides

Inoue, Hideo, Hayase, Yoji, Imura, Akihiro, Iwai, Shigenori, Miura, Kazunobu, Ohtsuka, Eiko

Journal:

Nucleic Acids Research

Year:

1987

Language:

english

File:

PDF, 874 KB

english, 1987

6

Effect of mutagenesis at each of five histidine residues on enzymatic activity and stability of ribonuclease H from Escherichia coli

Shigenori KANAYA, Katsuo KATAYANAGI, Kosuke MORIKAWA, Hideo INOUE, Eiko OHTSUKA, Morio IKEHARA

Journal:

Year:

1991

Language:

english

File:

PDF, 426 KB

english, 1991

7

Interaction of the Basic Protrusion ofEscherichia coliRibonuclease HI with its Substrate

Shigenori Iwai, Makoto Wakasa, Eiko Ohtsuka, Shigenori Kanaya, Akinori Kidera, Haruki Nakamura

Journal:

Journal of Molecular Biology

Year:

1996

Language:

english

File:

PDF, 302 KB

english, 1996

8

Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H

Hideo Inoue, Yoji Hayase, Shigenori Iwai, Eiko Ohtsuka

Journal:

Year:

1987

Language:

english

File:

PDF, 285 KB

english, 1987

9

Construction of a series of several self-cleaving RNA duplexes using synthetic 21-mers

Makoto Koizumi, Shigenori Iwai, Eiko Ohtsuka

Journal:

Year:

1988

Language:

english

File:

PDF, 306 KB

english, 1988

10

Cleavage of specific sites of RNA by designed ribozymes

Makoto Koizumi, Shigenori Iwai, Eiko Ohtsuka

Journal:

Year:

1988

Language:

english

File:

PDF, 534 KB

english, 1988

11

Kinetic analyses of DNA-linked ribonucleases H with different sizes of DNA

Eiko Kanaya, Yohtaro Uchiyama, Eiko Ohtsuka, Yoshio Ueno, Morio Ikehara, Shigenori Kanaya

Journal:

Year:

1994

Language:

english

File:

PDF, 665 KB

english, 1994

12

Sequence-specific cleavage of RNA by a hybrid ribonuclease H

Chieko Nakai, Aritomo Konishi, Yasuo Komatsu, Hideo Inoue, Eiko Ohtsuka, Shigenori Kanaya

Journal:

Year:

1994

Language:

english

File:

PDF, 658 KB

english, 1994

13

Recognition of 2′-hydroxyl groups by Escherichia coli ribonuclease HI

Shigenori Iwai, Shin Kataoka, Makoto Wakasa, Eiko Ohtsuka, Haruki Nakamura

Journal:

Year:

1995

Language:

english

File:

PDF, 717 KB

english, 1995

14

Studies of the interactions between Escherichia coli ribonuclease HI and its substrate

Yohtaro Uchiyama, Yasuhiro Miura, Hideo Inoue, Eiko Ohtsuka, Yoshio Ueno, Morio Ikehara, Shigenori Iwai

Journal:

Journal of Molecular Biology

Year:

1994

Language:

english

File:

PDF, 1.08 MB

english, 1994

15

An mRNA amplification procedure with directional cDNA cloning and strand-specific cRNA synthesis for comprehensive gene expression analysis

Satoko Ohtsuka, Katsuro Iwase, Masaki Kato, Naohiko Seki, Atsuko Shimizu-Yabe, Osamu Miyauchi, Eiko Sakao, Masaki Kanazawa, Shigenori Yamamoto, Yoichi Kohno, Masaki Takiguchi

Journal:

Year:

2004

Language:

english

File:

PDF, 850 KB

english, 2004

16

DNA-Linked RNase H For Site-Selective Cleavage Of RNA

Uchiyama, Yohtaro, Inoue, Hideo, Ohtsuka, Eiko, Nakai, Chieko, Kanaya, Shigenori, Ueno, Yoshio, Ikehara, Morio

Journal:

Bioconjugate Chemistry

Year:

1994

Language:

english

File:

PDF, 1.55 MB

english, 1994

17

Expression of a synthetic human growth hormone gene in yeast

Tomoko, Tokunaga, Shigenori, Iwai, Hideyuki, Gomi, Kazumi, Kodama, Eiko, Ohtsuka, Morio, Ikehara, Osamu, Chisaka, Kenichi, Matsubara

Journal:

Year:

1985

Language:

english

File:

PDF, 330 KB

english, 1985

18

5'-Levulinyl and 2'-tetrahydrofuranyl protection for the synthesis of oligoribonucleotides by the phosphoramidite approach

Iwai, Shigenori, Ohtsuka, Eiko

Journal:

Nucleic Acids Research

Year:

1988

Language:

english

File:

PDF, 713 KB

english, 1988

19

Cloning a defined region of DNA using a limited action of DNA polymerase: application to dissection of hepatitis B virus surface antigen gene

Osamu, Chisaka, Shigenori, Iwai, Eiko, Ohtsuka, Kenichi, Matsubara

Journal:

Year:

1986

Language:

english

File:

PDF, 801 KB

english, 1986

20

Molecular Cloning and Sequence Determination of cDNAs for α Subunits of the Guanine Nucleotide-Binding Proteins Gs, Gi, and Gofrom Rat Brain

Hiroshi Itoh, Tohru Kozasa, Shigekazu Nagata, Shun Nakamura, Toshiaki Katada, Michio Ui, Shigenori Iwai, Eiko Ohtsuka, Hiroshi Kawasaki, Koichi Suzuki and Yoshito Kaziro

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 1.15 MB

english, 1986

21

Solution Structure of an RNA·2‘- O -Methylated RNA Hybrid Duplex Containing an RNA·DNA Hybrid Segment at the Center †,‡

Nishizaki, Tomoko, Iwai, Shigenori, Ohtsuka, Eiko, Nakamura, Haruki

Journal:

Year:

1997

Language:

english

File:

PDF, 216 KB

english, 1997

22

Raman spectral studies of nucleic acids. 36. Structure in solution of the RNA.cntdot.DNA hybrid (rA)8.cntdot.(dT)8 determined by NMR and Raman spectroscopy

Katahira, Masato, Lee, Sang Jong, Kobayashi, Yuji, Sugeta, Hiromu, Kyogoku, Yoshimasa, Iwai, Shigenori, Ohtsuka, Eiko, Benevides, James M., Thomas, George J.

Journal:

Journal of the American Chemical Society

Year:

1990

Language:

english

File:

PDF, 749 KB

english, 1990

23

Solution Structures of DNA Duplexes Containing a DNA·RNA Hybrid Region, d(GG)r(AGAU)d(GAC)·d(GTCATCTCC) and d(GGAGA)r(UGAC)·d(GTCATCTCC) †,‡

Nishizaki, Tomoko, Iwai, Shigenori, Ohkubo, Tadayasu, Kojima, Chojiro, Nakamura, Haruki, Kyogoku, Yoshimasa, Ohtsuka, Eiko

Journal:

Year:

1996

Language:

english

File:

PDF, 568 KB

english, 1996

24

Synthesis of a Phosphoramidite Coupling Unit of the Pyrimidine (6−4) Pyrimidone Photoproduct and Its Incorporation into Oligodeoxynucleotides

Iwai, Shigenori, Shimizu, Masato, Kamiya, Hiroyuki, Ohtsuka, Eiko

Journal:

Journal of the American Chemical Society

Year:

1996

Language:

english

File:

PDF, 131 KB

english, 1996

25

Endonuclease V from Bacteriophage T4 Interacts with Its Substrate in the Minor Groove

Iwai, Shigenori, Maeda, Mie, Shimada, Yasuaki, Hori, Naoko, Murata, Tetsuya, Morioka, Hiroshi, Ohtsuka, Eiko

Journal:

Year:

1994

Language:

english

File:

PDF, 1.79 MB

english, 1994

26

Reaction mechanism of T4 endonuclease V determined by analysis using modified oligonucleotide duplexes

Iwai, Shigenori, Maeda, Mie, Shirai, Miho, Shimada, Yasuaki, Osafune, Tatsuya, Murata, Tetsuya, Ohtsuka, Eiko

Journal:

Year:

1995

Language:

english

File:

PDF, 2.09 MB

english, 1995

27

Design of RNA enzymes distinguishing a single base mutation in RNA

Koizumi, Makoto, Hayase, Yoji, Iwai, Shigenori, Kamiya, Hiroyuki, Inoue, Hideo, Ohtsuka, Eiko

Journal:

Nucleic Acids Research

Year:

1989

Language:

english

File:

PDF, 569 KB

english, 1989

28

Binding of nucleic acids to E.coli RNase HI observed by NMR and CD spectroscopy

Oda, Yasushi, Iwa, Shigenori, Ohtsuka, Eiko, Ishikawa, Momoyo, Ikehara, Morio, Nakamura, Haruki

Journal:

Nucleic Acids Research

Year:

1993

Language:

english

File:

PDF, 620 KB

english, 1993

29

A new solid-phase synthesis of oligoribonudeotides by the pbosphoro- p -anisidate method using tetrahydrofuranyl protection of 2'-hydroxyl groups

Jwai, Shigenori, Yamada, Emi, Asaka, Miyuki, Hayase, Yoji, Inoue, Hideo, Ohtsuka, Eiko

Journal:

Nucleic Acids Research

Year:

1987

Language:

english

File:

PDF, 883 KB

english, 1987

30

Cyclobutane thymine dimers in a ras proto-oncogene hot spot activate the gene by point mutation

Kamiya, Hiroyuki, Murata, Naoko, Murata, Tetsuya, Iwai, Shigenori, Matsukage, Akio, Masutani, Chikahide, Hanaoka, Fumio, Ohtsuka, Eiko

Journal:

Nucleic Acids Research

Year:

1993

Language:

english

File:

PDF, 3.95 MB

english, 1993

31

Synthesis and characterization of a substrate for T4 endonuclease V containing a phosphorodithioate linkage at the thymine dimer site

Murata, Tetsuya, Iwai, Shigenori, Ohtsuka, Eiko

Journal:

Nucleic Acids Research

Year:

1990

Language:

english

File:

PDF, 2.40 MB

english, 1990

32

How Does RNase H Recognize a DNA·RNA Hybrid?

Haruki Nakamura, Yasushi Oda, Shigenori Iwai, Hideo Inoue, Eiko Ohtsuka, Shigenori Kanaya, Shigenobu Kimura, Chieko Katsuda, Katsuo Katayanagi, Kosuke Morikawa, Hirotsugu Miyashiro and Morio Ikehara

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.38 MB

english, 1991

33

A kinetic study of hydrolysis of .BETA.-arylaminoacrolein derivatives.

ONO, MACHIKO, OHTSUKA, SHIGENORI, TAMURA, SHINZO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1983

File:

PDF, 749 KB

1983

34

Deoxyribonucleic acids (DNA) and related compounds. XIII. Synthesis of DNA duplexes containing a ribosome binding site.

OHTSUKA, EIKO, IWAI, SHIGENORI, TOKUNAGA, TOMOKO, IKEHARA, MORIO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1985

File:

PDF, 598 KB

1985

35

Synthesis of a gene coding for human lysozyme.

IKEHARA, MORIO, JUJIMOTO, KAZUKO, AOYAMA, YOSHIYUKI, YANASE, KOICHI, KATSUGI, JITSUHIRO, INEOKA, TETSUYA, TOKUNAGA, TOMOKO, UESUGI, SEIICHI, IWAI, SHIGENORI, OHTSUKA, EIKO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1986

File:

PDF, 592 KB

1986

36

Deoxyribonucleic acids and related compounds. XXII Synthesis of genes for human nerve growth factor and its fused protein.

IWAI, SHIGENORI, IMURA, AKIHIRO, INOUE, YASUHIKO, INOUE, HIDEO, MIURA, KAZUNOBU, TOKUNAGA, TOMOKO, IKEHARA, MORIO, OHTSUKA, EIKO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1986

File:

PDF, 1024 KB

1986

37

Synthesis and properties of hexanucleotides containing deoxyinosine.

KAWASE, YASUTOSHI, IWAI, SHIGENORI, OHTSUKA, EIKO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1988

File:

PDF, 454 KB

1988

38

Synthesis and thermal stability of dodecadeoxyribonucleotides containing deoxyinosine pairing with four major bases.

KAWASE, Yasutoshi, IWAI, Shigenori, OHTSUKA, Eiko

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1989

File:

PDF, 561 KB

1989

39

Synthesis of wobble pairing oligoribonucleotides.

KAWASE, Yasutoshi, KOIZUMI, Makoto, IWAI, Shigenori, OHTSUKA, Eiko

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1989

File:

PDF, 786 KB

1989

40

Deoxyribonucleic acids and related compounds. VIII. Solid-phase synthesis of deoxyribooligonucleotides with 3'-modification by elongation in the 3'-direction.

OHTSUKA, EIKO, TANIYAMA, YOSHIO, IWAI, SHIGENORI, YOSHIDA, TADAO, IKEHARA, MORIO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1984

File:

PDF, 767 KB

1984

41

A new solid-phase synthesis of ribooligonucleotides using the 3'-phosphoro-p-anisidate protecting group for stepwise synthesis in the 3'-direction.

Iwai, Shigenori, Asaka, Miyuki, Inoue, Hideo, Ohtsuka, Eiko

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1985

File:

PDF, 360 KB

1985

42

Uterine Cervical Cytology

Ohtsuka, Shigenori, Suto, Yuka, Tanaka, Shoko, Imai, Yuko, Shiromizu, Kenji, Shimizu, Ken, Toma, Mitsuyuki, Shibosawa, Toshiyuki

Year:

2014

File:

PDF, 1.21 MB

2014

43

Evolutionary transformation of mouthparts from particle-feeding to piercing carnivory in Viper copepods: Review and 3D analyses of a key innovation using advanced imaging techniques

Kaji, Tomonari, Song, Chihong, Murata, Kazuyoshi, Nonaka, Shigenori, Ogawa, Kota, Kondo, Yusuke, Ohtsuka, Susumu, Palmer, A. Richard

Journal:

Frontiers in Zoology

Year:

2019

Language:

english

File:

PDF, 31.38 MB

english, 2019